Tag Archives: SSRI Use In Pregnancy

Antidepressant Birth Defects and The First Amendment

The big shift in thinking about antidepressant use in pregnancy began in late 2005, when the FDA warned that Paxil "increases the risk for birth defects, particularly heart defects, when women take it during the first three months of pregnancy," and demanded  GlaxoSmithKline to change Paxil from a "Category C" drug to a "Category D" drug, i.e. a drug known to produce birth defects or injure fetuses.   In February 2006, the landmark "Selective Serotonin-Reuptake Inhibitors and Risk of Persistent Pulmonary Hypertension of the Newborn (PPHN)" study was published in the New England Journal of Medicine, showing that Prozac use in ... Continue Reading

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